2810379750 bmi@hmu.gr

HarmonicSS

 

Category European
Project Title HARMONIzation and integrative analysis of regional, national and international Cohorts on primary Sjögren’s Syndrome (pSS) towards improved stratification, treatment and health policy making
Funding Organization EC
Programme H2020, No 731944
Coordinator National and Kapodistrian University of Athens (short name: UoA) – Greece
Partners
  • Institute of Communication and Computer Systems (short name: ICCS) – Greece
  • University of Ioannina (short name: UOI) – Greece
  • Technological Educational Institute of Crete (short name: TEIC) – Greece
  • Centre for Research and Technology Hellas (short name: CERTH) – Greece
  • Universita Degli Studi di Udine (short name: DSMB) – Italy
  • Universita di Pisa (short name: UNIPI) – Italy
  • Universita Degli Studi di Perugia (short name: UNIPG) – Italy
  • Universita Degli Studi Dell’Aquila (short name: UNIVAQ) – Italy
  • Universita Degli Studi di Roma La Sapienza (short name: SAPIENZA Roma) – Italy
  • Scuola Superiore di Studi Universitari e di Perfezionamento Sant’Anna (short name: SSSA) – Italy
  • Medizinichen Hochshule Hannover (short name: MHH) – Germany
  • Charite – Universitatsmedizin Berlin (short name CHARITE) – Germany
  • Fraunhofer Gesellschaft zur Forderung der Angewandten Forschhung Ev (short name: Fraunhofer) – Germany
  • Gottfried Wilhelm Leibniz Universitaet Hannover (short name: LUH) – Germany
  • The University of Birmingham (short name: UoB) – United Kingdom
  • Queen Mary University of London (short name: QMUL) – United Kingdom
  • University of Newcastle upon Tyne (short name: UNEW) – United Kingdom
  • Consorci Institut D’Investigacions Biomediques August Pi I Sunyer (short name: IDIBAPS) – Spain
  • Fundacion Para La Investigacion E Innovacion Biomedica de Atencion Primaria (short name: FIIBAP) – Spain
  • Atos Spain SA (short name: ATOS SPAIN SA) – Spain
  • Universite De Bretagne Occidentale (short name: UBO) – France
  • Universite Paris – Sud (short name: UPSud) – France
  • Lunds Universitet (short name: ULUND) – Sweden
  • Uppsala Universitet (short name: UU) – Sweden
  • Academisch Ziekenhuis Groningen (short name: RUG) – Netherlands
  • Universitair Medisch Centrum Utrecht (short name: UMC UTRECHT) – Netherlands
  • Netherlands Institute for Health Services Research (short name: NIVEL) – Netherlands
  • European League against Rheumatism Standing Committee of People with Arthritis and Rheumatism (short name: EULAR) – Switzerland
  • Universitetet I Bergen (short name: UiB) – Norway
  • Univesite Libre de Bruxelles (short name: ULB) – Belgium
  • Bioirc D.O.O. Kragujevac (short name: BioIRC) – Serbia
  • Oklahoma Medical Research Foundation (short name: OMRF) – USA
  • Sjogren’s Syndrome Foundation (short name: SSF) – USA
  • Marios Lymarakis & SIA EE (short name: EXELIXIS) – Greece
Duration 01/01/2017 – 31/12/2020 (48 months)
Total Budget 9.998.750,00 €
TEI-Crete budget 202.500,00 €
Web Site  http://harmonicss.eu
Project Objective HarmonicSS vision is to create an International Network and Alliance of partners and cohorts, entrusted with the mission of addressing the unmet needs in primary Sjogren Syndrome; working together to create and maintain a platform with open standards and tools, designed to enable secure storage, governance, analytics, access control and controlled sharing of information at multiple levels along with methods to make results of analyses and outcomes comparable across centers and sustainable through Rheumatology associations. The overall idea of the HarmonicSS project is to bring together the largest well characterized regional, national and international longitudinal cohorts of patients with Primary Sjögren’s Syndrome (pSS) including those participating in clinical trials, and after taking into consideration the ethical, legal, privacy and IPR issues for sharing data from different countries, to semantically interlink and harmonize them into an integrative pSS cohort structure on the cloud. Upon this harmonized cohort, services for big data mining, governance and visual analytics will be integrated, to address the identified clinical and health policy pSS unmet needs. In addition, tools for specific diagnostic procedures (e.g. ultrasonography image segmentation), patient selection for clinical trials and training will be also provided. The users of the HarmonicSS platform are researchers (basic/translational), clinicians, health policy makers and pharma companies. pSS is relevant not only due to its clinical impact but also as one of the few “model” diseases to link autoimmunity, cancer development (lymphoproliferation) and the pathogenetic role of infection. Thus, the study of pSS can facilitate research in many areas of medicine; for this reason, the possibility for sustainability and expandability of the platform is enhanced. Moreover, pSS has a significant impact on the healthcare systems, similar to that of rheumatoid arthritis.